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Human IL-6 Animal-Free Recombinant Protein

Human IL-6 Animal-Free Recombinant Protein
Human IL-6 Animal-Free Recombinant Protein
Human IL-6 Animal-Free Recombinant Protein
New
Human IL-6 Animal-Free Recombinant Protein
Human IL-6 Animal-Free Recombinant Protein
Human IL-6 Animal-Free Recombinant Protein
Human IL-6 Animal-Free Recombinant Protein
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$64.00
Ex Tax: $64.00
  • Stock: In Stock
  • Model: 0673
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Product Description

IL-6 is a multifaceted cytokine pivotal in host defense, orchestrating immune and inflammatory responses. It's generated by T cells, monocytes, fibroblasts, endothelial cells, and keratinocytes, showcasing a wide array of biological functions. IL-6 promotes B cell differentiation and antibody production, collaborates with IL-3 in megakaryocyte development and platelet production, triggers the expression of hepatic acute-phase proteins, and governs bone metabolism.

IL-6 communicates through the IL-6 receptor system composed of two chains: IL-6Rα and gp130. Notably, murine IL-6 lacks activity on Human cells, while both Human and murine variants are equally effective on murine cells. The recombinant Human IL-6 is a 20.9 kDa protein encompassing 184 amino acid residues.

 

Product Specifications

  
Species Human
Published species

Human, Mouse
Expression System E. coli
Amino acid sequence

PVPPGEDSKD VAAPHRQPLT SSERIDKQIR YILDGISALR KETCNKSNMC ESSKEALAEN NLNLPKMAEK DGCFQSGFNE ETCLVKIITG LLEFEVYLEY LQNRFESSEE QARAVQMSTK VLIQFLQKKA KNLDAITTPD PTTNASLLTK LQAQNQWLQD MTTHLILRSF KEFLQSSLRA LRQM
Molecular weight 20.9 kDa
Class Recombinant
Type Protein
Purity

≥ 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin concentration <0.1 EU/µg
Activity

Determined by its ability to stimulate the proliferation of mouse B9 cells. ED50 is 0.003 - 0.005 ng/ml.
Conjugate Unconjugated
Form Lyophilized
Contains

no preservative
Storage conditions -20°C

CAUTION

For Research Use Only. Not for use in diagnostic procedures.

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Animal Free Recombinant Human IL-6 COA.pdf 95.72KB 41
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