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Human GM-CSF Animal-Free Recombinant Protein

Human GM-CSF Animal-Free Recombinant Protein
Human GM-CSF Animal-Free Recombinant Protein
Human GM-CSF Animal-Free Recombinant Protein
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Human GM-CSF Animal-Free Recombinant Protein
Human GM-CSF Animal-Free Recombinant Protein
Human GM-CSF Animal-Free Recombinant Protein
Human GM-CSF Animal-Free Recombinant Protein
$66.00
Ex Tax: $66.00
  • Stock: In Stock
  • Model: 0674

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Product Description

GM-CSF, a hematopoietic growth factor, plays a role in stimulating the development of neutrophils and macrophages while also supporting the proliferation and maturation of early erythroid, megakaryocytic, and eosinophilic progenitor cells. It's primarily produced in endothelial cells, monocytes, fibroblasts, and T-lymphocytes. GM-CSF has the additional effect of inhibiting neutrophil migration and boosting the functional activity of mature end cells. Unlike G-CSF, GM-CSF molecules are species-specific with no cross-reactivity between Human and murine versions. Recombinant Human GM-CSF is a 14.6 kDa globular protein comprising 128 amino acids, featuring two intramolecular disulfide bonds and two potential N-linked glycosylation sites.

 

Product Specifications

 
Species Human
Published species

Human, Mouse

Expression System E. coli
Amino acid sequence

MAPARSPSPS TQPWEHVNAI QEARRLLNLS RDTAAEMNET VEVISEMFDL QEPTCLQTRL ELYKQGLRGS LTKLKGPLTM MASHYKQHCP PTPETSCATQ IITFESFKEN LKDFLLVIPF DCWEPVQE

Molecular weight 14.6 kDa
Class Recombinant
Type Protein
Purity

≥ 98% by SDS-PAGE gel and HPLC analyses.

Endotoxin concentration <0.1 EU/µg
Activity

The ED50, determined by the dose-dependent stimulation of human TF-1 cell proliferation, is between 0.12 and 0.18 ng/ml. 

Conjugate Unconjugated
Form Lyophilized
Contains

no preservative

Storage conditions -20°C

CAUTION

For Research Use Only. Not for use in diagnostic procedures.

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Animal Free Recombinant Human GM-CSF COA.pdf 94.02KB 14