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Human BMP-4 Animal-Free Recombinant Protein

Human BMP-4 Animal-Free Recombinant Protein
Human BMP-4 Animal-Free Recombinant Protein
New
Human BMP-4 Animal-Free Recombinant Protein
Human BMP-4 Animal-Free Recombinant Protein
Human BMP-4 Animal-Free Recombinant Protein
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$84.00
Ex Tax: $84.00
  • Stock: In Stock
  • Model: 0675
HYGIA HYGIA

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Product Description

Bone morphogenetic proteins (BMPs) belong to the TGF-β superfamily, a group of structurally related signaling proteins. This superfamily is widely distributed in the body and plays diverse roles during prenatal and postnatal life. Like BMP-7, BMP-4 contributes significantly to bone and cartilage development and maintenance. Reduced BMP-4 expression is linked to various bone disorders, including Fibrodysplasia Ossificans Progressiva, an inherited condition.

E.coli-derived BMP-4 is a fully active homodimeric protein consisting of two 106 amino acid subunits, corresponding to amino acids 303-408 of the full-length BMP-4 precursor. The calculated molecular weight of Recombinant Human BMP-4 (E.coli-derived) is 23.9 kDa.

 

Product Specifications

  
Species Human
Published species

Human, Mouse, Rat
Expression System

E.Coli
Amino acid sequence KKNKNCRRHS LYVDFSDVGW NDWIVAPPGY QAFYCHGDCP FPLADHLNST NHAIVQTLVN SVNSSIPKAC CVPTELSAIS MLYLDEYDKV VLKNYQEMVV EGCGCR
Molecular weight 23.9 kDa
Class Recombinant
Type Protein
Purity

≥ 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin concentration <0.1 EU/µg
Activity

Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 for this effect is 2-8 ng/ml.
Conjugate Unconjugated
Form Lyophilized
Contains

no preservative
Storage conditions -20°C

CAUTION

For Research Use Only. Not for use in diagnostic procedures.

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Animal Free Recombinant Human BMP4 COA.pdf 93.93KB 15
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