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Human beta-NGF Animal-Free Recombinant Protein

Human beta-NGF Animal-Free Recombinant Protein
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Human beta-NGF Animal-Free Recombinant Protein
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$20.00
Ex Tax: $20.00
  • Stock: In Stock
  • Model: 0665
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Product Description

β-NGF, a neurotrophic factor structurally akin to BDNF, NT-3, and NT-4, is part of the cysteine-knot family of growth factors, characterized by stable dimeric structures. This potent neurotrophic factor operates via its receptor β-NGFR, playing a pivotal role in the development and maintenance of the sensory and sympathetic nervous systems. Additionally, β-NGF functions as a growth and differentiation factor for B lymphocytes, boosting B-cell survival. The active form of Recombinant Human β-NGF is a non-covalently linked homodimer comprising two 13.5 kDa polypeptide monomers, each containing 120 amino acids and three disulfide bonds essential for biological activity.

 

Product Specifications

  
Species Human
Published species Human, Rat
Expression System E. coli
Amino acid sequence

SSSHPIFHRG EFSVCDSVSV WVGDKTTATD IKGKEVMVLG EVNINNSVFK QYFFETKCRD PNPVDSGCRG IDSKHWNSYC TTTHTFVKAL TMDGKQAAWR FIRIDTACVC VLSRKAVRRA
Molecular weight 27 kDa
Class Recombinant
Type Protein
Purity

≥ 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin concentration <0.1 EU/µg
Activity

Determined by the dose-dependent stimulation of the proliferation of human TF-1 cells. The expected ED50 is ≤ 1.0 ng/ml, corresponding to a specific activity of ≥ 1 x 10^6 units/mg.
Conjugate Unconjugated
Form Lyophilized
Contains

no preservative
Storage conditions -20°C

CAUTION

For Research Use Only. Not for use in diagnostic procedures.

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Animal Free Recombinant Human Beta NGF COA.pdf 110.01KB 19
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