Human BDNF Animal-Free Recombinant Protein
- Stock: In Stock
- Model: 0682
Available Options
Product Description
BDNF belongs to the NGF family of neurotrophic growth factors, supporting neuron growth and survival. It binds to a low-affinity cell surface receptor, LNGFR, shared with other neurotrophins like NGF, NT-3, and NT-4. However, BDNF primarily exerts its neurotrophic effects through the high-affinity receptor gp145/trkB. Structurally, BDNF is part of a 247 amino acid polypeptide precursor, featuring an 18 amino acid signal sequence and a 110 amino acid propeptide. Recombinant Human/Murine/Rat BDNF exists as a 27.0 kDa homodimer comprising two 120 amino acid subunits held together by robust non-covalent interactions.
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Product Specifications |
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| Species |
Human, Mouse, Rat |
| Published species |
Amphibian, Chicken, Human, Mouse, Non-human primate, Rat |
| Expression System | E. coli |
| Amino acid sequence |
MHSDPARRGE LSVCDSISEW VTAADKKTAV DMSGGTVTVL EKVPVSKGQL KQYFYETKCN PMGYTKEGCR GIDKRHWNSQ CRTTQSYVRA LTMDSKKRIG WRFIRIDTSC VCTLTIKRGR |
| Molecular weight | 27.0 kDa |
| Class | Recombinant |
| Type | Protein |
| Purity |
≥ 98% by SDS-PAGE gel and HPLC analyses. |
| Endotoxin concentration | <0.1 EU/µg |
| Activity | ED50 is 1.7 - 2.6 ug/ml of h-BDNF using C6 cell line. |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Contains |
no preservative |
| Storage conditions | -20°C |
CAUTION
For Research Use Only. Not for use in diagnostic procedures.
| Thumb | File information |
| Animal Free Recombinant Human BDNF COA.pdf File Size94.4KB Downloaded: 44 |