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Human BDNF Animal-Free Recombinant Protein

Human BDNF Animal-Free Recombinant Protein
Human BDNF Animal-Free Recombinant Protein
Human BDNF Animal-Free Recombinant Protein
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Human BDNF Animal-Free Recombinant Protein
Human BDNF Animal-Free Recombinant Protein
Human BDNF Animal-Free Recombinant Protein
Human BDNF Animal-Free Recombinant Protein
$108.00
Ex Tax: $108.00
  • Stock: In Stock
  • Model: 0682

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Product Description

BDNF belongs to the NGF family of neurotrophic growth factors, supporting neuron growth and survival. It binds to a low-affinity cell surface receptor, LNGFR, shared with other neurotrophins like NGF, NT-3, and NT-4. However, BDNF primarily exerts its neurotrophic effects through the high-affinity receptor gp145/trkB. Structurally, BDNF is part of a 247 amino acid polypeptide precursor, featuring an 18 amino acid signal sequence and a 110 amino acid propeptide. Recombinant Human/Murine/Rat BDNF exists as a 27.0 kDa homodimer comprising two 120 amino acid subunits held together by robust non-covalent interactions.

 

Product Specifications

 
Species

Human, Mouse, Rat

Published species

Amphibian, Chicken, Human, Mouse, Non-human primate, Rat

Expression System E. coli
Amino acid sequence

MHSDPARRGE LSVCDSISEW VTAADKKTAV DMSGGTVTVL EKVPVSKGQL KQYFYETKCN PMGYTKEGCR GIDKRHWNSQ CRTTQSYVRA LTMDSKKRIG WRFIRIDTSC VCTLTIKRGR

Molecular weight 27.0 kDa
Class Recombinant
Type Protein
Purity

≥ 98% by SDS-PAGE gel and HPLC analyses.

Endotoxin concentration <0.1 EU/µg
Activity ED50 is 1.7 - 2.6 ug/ml of h-BDNF using C6 cell line.
Conjugate Unconjugated
Form Lyophilized
Contains

no preservative

Storage conditions -20°C

CAUTION

For Research Use Only. Not for use in diagnostic procedures.

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Thumb File information
Animal Free Recombinant Human BDNF COA.pdf 94.4KB 17