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Brand: HYGIA
IntroductionCell-free DNA (or cfDNA) refers to all non-encapsulated double-stranded extracellular DNA fragments in the bloodstream and other bodily fluids, such as circulating tumor DNA (ctDNA), cell-free mitochondrial DNA (ccf mtDNA), and cell-free fetal DNA (cfDNA). This DNA is released into the b..
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Brand: HYGIA
IntroductionThe presence of protein and lipids in biological fluid samples frequently interferes with small molecule analysis, decreasing accuracy and sensitivity. Numerous bioassays need the removal of proteins (deproteinization) and lipids (delipidation) from samples before analysis, such as LC/MS..
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Brand: HYGIA
IntroductionDetergents contain a hydrophilic head group and a hydrophobic tail. The hydrophobic moiety usually consists of a hydrocarbon chain, while the hydrophilic part has a polar head. Three types of detergents are commonly used in laboratory research, including:● Non-ionic detergents contain un..
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Brand: HYGIA
IntroductionHygia One-Step DNA & RNA Cleanup Kit provides one-step removal of impurity by negative chromatography from pre-purified samples of DNA/RNA. The impurity includes DNA/RNA polymerases, modifying enzymes, restriction endonucleases, ligases, kinases, nucleases, phosphatases, protein..
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Brand: HYGIA
IntroductionHygia One-Step DNA & RNA Removal Kit uses endonuclease -immobilized magnetic beads to remove DNA and RNA from sample using a single step protocol. The recombinant endonuclease is encoded by the same gene of Merck Benzonase nuclease or TurboNuclease) of Serratia macescens produce..
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Brand: HYGIA
IntroductionFluorescent dyes, also called reactive dyes or fluorophores, are natural or synthetic compounds that absorb light and re-emit it at a longer wavelength. Due to their unique advantages such as versatility, sensitivity, and quantitative capabilities, fluorescent dyes are widely used to lab..
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Brand: HYGIA
IntroductionFormalin fixation and paraffin embedding (FFPE) tissues and Fine-needle Aspiration Biopsy (FNA) are popular sources of archival tissue samples that pathologists have used for decades. It enables long-term, room-temperature preservation of tissue samples, making it extremely handy. Becaus..
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Brand: HYGIA
IntroductionBones and teeth are frequently the only DNA samples for identifying human remains. The purification of DNA from bones and teeth is important in many molecular biology applications, including forensic analysis, ancient DNA analysis, and genetic studies. The effective extraction of DNA fro..
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Brand: HYGIA
IntroductionThe Significance of Hair in Forensics and Medical ResearchHair is one of the most commonly found evidence at crime scenes and is gaining importance as a sample type for medical research inquiries. In criminology, hair has been used for population-based statistical analysis and DNA-based ..
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Brand: HYGIA
IntroductionSexual assault cases (also called Rape cases) are some of the most challenging and sensitive cases for forensic scientists and law enforcement. Sexual assault cases require a clear male DNA profile in order to analyze autosomal DNA. However, mixed DNA samples collected from female victim..
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Brand: HYGIA
IntroductionBiotin, also referred to as vitamin H, is a small molecule that is not commonly found in biological samples. It has a remarkable binding affinity for avidin (Ka=10^15) and streptavidin (Ka=10^14), making biotinylated molecules such as proteins or other molecules very useful for non-radio..
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